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Home > Studies > In Breast Cancer > BCIRG 004
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BCIRG 004
Study: BCIRG 004
| Title |
Clinical protocol for a phase II double-blind evaluation of G-CSF vs the optimal schedule of SC-70935 in patients with breast cancer receiving chemotherapy with docetaxel, doxorubicin and cyclophosphamide (TAC) |
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Sponsor |
Searle Research and Development (Pharmacia and Upjohn) |
| Rationale |
TAC is associated with a relatively high incidence of febrile neutropenia when given without prophylactic hematopoetic growth factor support. This study compared two compounds for the reduction of febrile neutropenia when given as prophylaxis. |
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| Design |
TAC  |
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| G-CSF (Neupogen) 5 mg/kg once daily | |
| SC-70935 10 mg/kg every other day | |
| SC-70935 5 mg/kg once daily | | |
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Number of Patients |
451 patients |
| Status |
Final Results Published |
Paper and Poster: |
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